star trek - How do Hypo-sprays work?

In Star Trek, the hypo-spray is the replacement of the syringe in our time frame. But does the hypo-spray actually pierce the skin?

I've seen times when they are used on direct skin contact, through clothes, into a bio-bag-thingy (Voyager), and even into open air like an aerosol can.

Is the medication merely absorbed through the skin? Does it pierce the skin? Do the patients feel pain that they are bravely hiding?

Answer

As Wikis pointed out, the standard hypospray does not pierce the skin. Their standard mode of operation is similar to the jet injector he mentioned.

They do, however, have other modes of operation - they can dispense aerosol medications. They also have the ability to collect atmospheric samples or store compressed gasses. They can also inject through clothing.

Memory Alpha has more information.

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