marvel - How does the Muramasa Blade block Wolverine's regeneration capability?

Wolverine's mutant powers can't heal him faster if he is wounded by the red Muramasa Blade (not the old black).

From the linked Wiki:

In a subsequent fight with Captain America, the sword was used against Wolverine, leaving a scar on his chest, which oddly didn't heal as usual. After the fight was over, Wolverine gave the sword to Cyclops, explaining it by saying: "This is the only thing in the world that can put me down for good."

Muramasa Blade

I want to know how this blade works such that it can block the regeneration powers of Wolverine.

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