In Ender's Game , is Ender genetically engineered (along with Peter and Valentine) or are they just naturally gifted? Answer From Wikipedia Genetic engineering, also called genetic modification, is the direct human manipulation of an organism's genetic material in a way that does not occur under natural conditions. It involves the use of recombinant DNA techniques, but does not include traditional animal and plant breeding or mutagenesis. If I recall correctly, Ender's parents were assigned to one another, so he was the result of a breeding program, but not genetic engineering.