In the TNG episode The Enemy, Worf ends up being the only viable donor available to save the life of an injured Romulan.
Crusher: "Worf, you are the only one who can save his life."
Worf: "Then he will die."
Surely a Vulcan would be a superior match for obtaining vital bodily fluids. And with a crew compliment of 1,014 members there wasn't a single Vulcan serving on the Enterprise-D?
Worf: "There is a substance within my cells which you need to survive."
Patahk: "Then you've come to hear me beg for my life?"
Worf: "No."
Patahk: "I would rather die than pollute my body with Klingon filth!"
Answer
There were Vulcans on board during that episode, and they weren't compatible donors:
CRUSHER: My patient is not responding to treatment.
PICARD: You haven't found a compatible ribosome donor?
CRUSHER: The lab is still processing the tests. Early results indicate humans have far too many bio-rejection factors. I've also ruled out the Vulcans we've tested.
The only direct explanation given for how Worf could be more compatible than the Vulcans is some vagueness about how "many humanoids have comparable cell structures."
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